Toxicological parameters of the drug based on Ornidazole and Levamisole hydrochloride
نویسندگان
چکیده
The purpose of the research is study pharmaco-toxicological properties Ornidazole- and Levamisole hydrochloride-based drug. Materials methods . drug were studied in premises Laboratory Preclinical Studies, Faculty Veterinary Medicine, Stavropol State Agrarian University. Acute chronic toxicity, irritant effect was under Guidelines for Studies Drugs (2012). Hematological studies laboratory animals performed with an automatic hematological analyzer, biochemical blood serum done analyzer. Results discussion It has been found that belongs to Hazard Class 3 median lethal oral dose accordance GOST 12.1.007–76 as moderately hazardous substances; it does not have a pronounced subchronic toxicity or effect. Multiple use active substance 14 days cause significant changes clinical condition, profile animals.
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ژورنال
عنوان ژورنال: Rossii?skii? Parazitologicheskii? Zhurnal
سال: 2023
ISSN: ['1998-8435', '2541-7843']
DOI: https://doi.org/10.31016/1998-8435-2022-16-4-421-431